The CpxRA Two-Component System Is Essential for Citrobacter rodentium Virulence
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چکیده
منابع مشابه
Role of RpoS in the virulence of Citrobacter rodentium.
Citrobacter rodentium is a mouse enteropathogen that is closely related to Escherichia coli and causes severe colonic hyperplasia and bloody diarrhea. C. rodentium infection requires expression of genes of the locus of enterocyte effacement (LEE) pathogenicity island, which simulates infection by enteropathogenic E. coli and enterohemorrhagic E. coli in the human intestine, providing an effecti...
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The mouse enteric pathogen Citrobacter rodentium, like its human counterpart, enteropathogenic Escherichia coli, causes attaching and effacing lesions in the intestinal epithelium of its host. This phenotype requires virulence factors encoded by the locus for enterocyte effacement (LEE) pathogenicity island. For timely expression of these virulence determinants at the site of infection and for ...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2015
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00194-15